Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29472390 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HSD17B10ALDH1A3VCAM1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL30783012 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HSD17B10ALDH1A3VCAM1ALDH3A1 | |
| SCHEMBL2009103 | 0.84 | KIF11 (0.54) | ALDH1A1HSD17B10PTGS2KIF11 | |
| SCHEMBL18002915 | 0.83 | AHR (0.46) | ALDH1A1HSD17B10ALDH1A3TRPA1KMT2A | |
| SCHEMBL4847293 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ALDH1A3VCAM1ALDH3A1 | |
| SCHEMBL190947 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10ALDH1A3VCAM1ALDH3A1 | |
| SCHEMBL8698264 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TTRKDM4EPTGS2RAB9A | |
| SCHEMBL18345531 | 0.79 | XDH (0.48) | ALDH1A1HSD17B10TRPA1KDM4ESLC2A1 | |
| SCHEMBL14989926 | 0.79 | XDH (0.48) | ALDH1A1HSD17B10TRPA1KDM4ESLC2A1 | |
| SCHEMBL3926234 | 0.79 | HSD17B10 (0.45) | ALDH1A1HSD17B10ALDH1A3VCAM1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598815-A | 2-Urea (thiourea) base-4-phenyl substituted quinazoline compound and preparation method and application thereof | 西华大学 | 2024-09-06 | — | — | CN | claimed |
| CN-118496215-A | Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof | 中国药科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-117624148-A | Polyhydroxy sulfonium salt derivative with disubstituted benzene ring, preparation method and medical application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | claimed |
| CN-112266352-B | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | claimed |
| CN-112266352-A | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2021-01-26 | — | — | CN | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| CN-107188851-B | Method for synthesizing astemizole key intermediate and derivative thereof | 湖南大学 | 2020-04-07 | — | — | CN | claimed |
| US-20180273906-A1 | MICROVESICLE AND STEM CELL COMPOSITIONS FOR THERAPEUTIC APPLICATIONS | IPS HEART | 2018-09-27 | — | — | US | claimed |
| US-10017684-B2 | Method and compositions for hydraulic fracturing and for tracing formation water | SPECTRUM TRACER SERVICES, LLC (US) | 2018-07-10 | — | — | US | claimed |
| EP-1773843-A4 | SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS | UNIV TEXAS (US) | 2009-06-03 | — | — | EP | claimed |
| EP-1773843-A1 | SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS | The Board of Regents of The University of Texas System (US) | 2007-04-18 | — | — | EP | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| WO-2006014404-A1 | SMALL MOLECULE THIENOPYRIMIDINE-BASED PROTEIN TYROSINE KINASE INHIBITORS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-02-09 | — | — | WO | claimed |
| US-20060004002-A1 | Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-01-05 | — | — | US | claimed |
| EP-0979812-B1 | Process for the preparation of fluorinated benzyl alcools and benzyl aldehydes | BAYER AG (DE) | 2003-10-29 | — | — | EP | claimed |
| EP-0903334-B1 | Halogenated aromatic derivatives and process for the preparation thereof | MITENI SPA (IT) | 2003-06-11 | — | — | EP | claimed |
| EP-0922693-B1 | Process for the preparation of 3-chloro-4-fluorobenzoyl chloride | CLARIANT GMBH (DE) | 2001-10-24 | — | — | EP | claimed |
| US-6127581-A | Process for preparing fluorinated benzyl alcohols and fluorinated benzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | claimed |
| EP-0979812-A1 | Process for the preparation of fluorinated benzyl alcools and benzyl aldehydes | Bayer Aktiengesellschaft (DE) | 2000-02-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004002-A1 | Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors | SRC, LCK, FYN | ALDH1A1 4583/4885HSD17B10 4240/4885ALDH1A3 4871/4885 |
| US-20180273906-A1 | MICROVESICLE AND STEM CELL COMPOSITIONS FOR THERAPEUTIC APPLICATIONS | EXOSC9, EXOSC5, EXOSC4 | ALDH1A1 493/4885HSD17B10 3195/4885ALDH1A3 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.