Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384677 | 0.78 | HPD (0.41) | HPGDALDH1A1SMN1; SMN2POLBHPD | |
| SCHEMBL9240067 | 0.77 | HPD (0.46) | HPGDALDH1A1SMN1; SMN2POLBHPD | |
| SCHEMBL1132003 | 0.76 | POLB (0.45) | HPGDALDH1A1SMN1; SMN2POLBHPD | |
| SCHEMBL9871935 | 0.75 | SMN1; SMN2 (0.48) | HPGDSMN1; SMN2POLBHPDCYP1A2 | |
| SCHEMBL8694806 | 0.75 | HPGD (0.42) | HPGDALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL8698285 | 0.75 | HPGD (0.42) | HPGDALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL8693826 | 0.74 | SMN1; SMN2 (0.46) | HPGDALDH1A1SMN1; SMN2HPDCYP1A2 | |
| SCHEMBL9814693 | 0.73 | SMN1; SMN2 (0.44) | HPGDALDH1A1SMN1; SMN2POLBHPD | |
| SCHEMBL9874527 | 0.73 | HPD (0.42) | HPGDALDH1A1SMN1; SMN2POLBHPD | |
| SCHEMBL9711504 | 0.73 | SMN1; SMN2 (0.41) | HPGDALDH1A1SMN1; SMN2POLBHPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |