SCHEMBL8698292

SCHEMBL8698292

CC(=NO)c1cccc(OCOCc2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.55
NR4A2 P43354 3/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMPD1 P17405 1/20 0.46
SRD5A2 P31213 1/20 0.45
MAOA P21397 3/20 0.44
PTPN1 P18031 1/20 0.44
NR1H4 Q96RI1 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
F10 P00742 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8697768 0.83 MAOB (0.78) MAOBNR4A2MEN1KMT2ASMPD1
SCHEMBL5501768 0.80 NR4A2 (0.77) MAOBNR4A2MEN1KMT2ASMPD1
SCHEMBL6155669 0.80 NPC1 (0.51) MAOBKMT2AMAOA
SCHEMBL6155665 0.80 NPC1 (0.51) MAOBKMT2AMAOA
SCHEMBL28768851 0.78 MAOB (0.58) MAOBNR4A2MEN1KMT2ASMPD1
SCHEMBL8697284 0.77 MAOB (0.73) MAOBNR4A2MAOA
SCHEMBL11019942 0.76 DRD2 (0.55) MAOBNR4A2MEN1KMT2AMAOA
SCHEMBL20342880 0.76 KMT2A (0.51) MEN1KMT2ANR1H4SMN1; SMN2
SCHEMBL3158759 0.75 TSHR (0.64) MAOBNR4A2MAOATSHRSMN1; SMN2
SCHEMBL9395985 0.75 MAOB (0.66) MAOBNR4A2SRD5A2MAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998017631-A2 SUBSTITUTED OXIME-ETHERS AND THEIR USE AS PESTICIDES NOVARTIS AG (CH) 1998-04-30 WO disclosed