Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697768 | 0.88 | MAOB (0.78) | NR4A2NR1H4SRD5A2MAOBMEN1 | |
| SCHEMBL30207018 | 0.87 | NR4A2 (1.00) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL339009 | 0.87 | NR4A2 (1.00) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL1123155 | 0.86 | NR4A2 (0.91) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL28768851 | 0.86 | MAOB (0.58) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.86 | NR4A2 (0.97) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL1122713 | 0.84 | NR4A2 (0.94) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL20472362 | 0.83 | NR4A2 (0.69) | NR4A2NR1H4SRD5A2MAOBMRGPRX4 | |
| SCHEMBL5017852 | 0.82 | PLA2G4B (0.56) | NR4A2MAOBKMT2ASMPD1FFAR1 | |
| SCHEMBL4138759 | 0.81 | NR4A2 (0.81) | NR4A2MRGPRX4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751097-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | Proteotech, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113489-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH, INC. (US) | 2005-12-01 | — | — | WO | disclosed |