Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 12/20 | 0.41 |
| ▸ | LDHB | P07195 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605314 | 0.81 | LDHA (0.47) | LDHALDHBALDH1A1 | |
| SCHEMBL6606098 | 0.80 | LDHA (0.54) | LDHALDHBALDH1A1 | |
| SCHEMBL6604139 | 0.77 | LDHA (0.48) | LDHALDHB | |
| SCHEMBL6604343 | 0.77 | LDHA (0.48) | LDHALDHB | |
| SCHEMBL8702422 | 0.77 | LDHA (0.52) | LDHALDHB | |
| SCHEMBL7758845 | 0.75 | LDHA (0.48) | LDHALDHB | |
| SCHEMBL6604694 | 0.75 | LDHA (0.54) | LDHALDHB | |
| SCHEMBL7448194 | 0.74 | LDHA (0.47) | LDHALDHB | |
| SCHEMBL8011472 | 0.74 | LDHA (0.47) | LDHALDHB | |
| SCHEMBL6607939 | 0.74 | LDHA (0.50) | LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834506-A | TREATMENT OF HIV, AIDS; ANTIVIRAL ACTIVITY IMPROVED BY JUDICIOUS PLACEMENT OF POLAR SUBSTITUENTS | WARNER-LAMBERT COMPANY (US) | 1998-11-10 | — | — | US | disclosed |