SCHEMBL8698574

SCHEMBL8698574

CC(C1CCCCN1CCCc1ccccc1)n1ccnc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8698582 0.99 CYP17A1 (0.41) CYP17A1SIGMAR1
SCHEMBL8698467 0.97 SIGMAR1 (0.41) CYP17A1SIGMAR1
SCHEMBL8696333 0.93 CYP17A1 (0.43) CYP17A1
SCHEMBL8699398 0.84 CYP19A1 (0.39)
SCHEMBL8695800 0.84 SIGMAR1 (0.41) SIGMAR1
SCHEMBL8698785 0.83 SIGMAR1 (0.40) SIGMAR1
SCHEMBL8698076 0.82 CYP17A1 (0.44) CYP17A1
SCHEMBL8699130 0.82 TBXAS1 (0.47)
SCHEMBL8701383 0.81 TBXAS1 (0.47) CYP17A1
SCHEMBL8696866 0.81 CYP17A1 (0.41) CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741800-A ANTIINFLAMMATORY AGENT, ANTIALLERGENS KNOLL AKTIENGESELLACHAFT (DE) 1998-04-21 US claimed
US-5741800-A ANTIINFLAMMATORY AGENT, ANTIALLERGENS KNOLL AKTIENGESELLACHAFT (DE) 1998-04-21 US disclosed