Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695530 | 0.89 | F2 (0.46) | F2STSMEN1KMT2AMAPT | |
| SCHEMBL8696210 | 0.89 | STS (0.45) | F2STSMEN1KMT2AMAPT | |
| SCHEMBL8694484 | 0.87 | F2 (0.62) | F2MEN1KMT2A | |
| SCHEMBL8695519 | 0.86 | STS (0.49) | STSMEN1KMT2AMAPTTP53 | |
| SCHEMBL8694486 | 0.84 | F2 (0.46) | F2MEN1KMT2ALMNA | |
| SCHEMBL8695575 | 0.82 | STS (0.46) | F2STSMEN1KMT2AMAPT | |
| SCHEMBL8698820 | 0.81 | STS (0.46) | F2STSMEN1KMT2ASCN9A | |
| SCHEMBL8700362 | 0.81 | F2 (0.46) | F2STSMEN1KMT2ASCN9A | |
| SCHEMBL8695762 | 0.79 | TP53 (0.44) | F2STSMEN1KMT2AMAPT | |
| SCHEMBL8698765 | 0.78 | HTR6 (0.46) | F2STSMEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |