Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
| ▸ | APLNR | P35414 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695519 | 0.91 | STS (0.49) | HTR6STSMEN1KMT2A | |
| SCHEMBL8700362 | 0.89 | F2 (0.46) | HTR6STSAPLNRF2F10 | |
| SCHEMBL8695451 | 0.85 | F2 (0.56) | HTR6F2F10PRSS2CTRC | |
| SCHEMBL8695452 | 0.81 | HTR6 (0.48) | HTR6F2F10PRSS2CTRC | |
| SCHEMBL8696210 | 0.80 | STS (0.45) | HTR6STSF2F10PRSS2 | |
| SCHEMBL8695530 | 0.78 | F2 (0.46) | STSF2POLBMEN1KMT2A | |
| SCHEMBL8695300 | 0.78 | F2 (0.56) | HTR6F2F10PRSS2CTRC | |
| SCHEMBL8698733 | 0.78 | F2 (0.47) | STSF2SCN9AMEN1KMT2A | |
| SCHEMBL7548937 | 0.76 | F2 (0.63) | HTR6F2F10PRSS2CTRC | |
| SCHEMBL23214857 | 0.75 | PDE4B (0.50) | STSSCN9AUSP30HPGDSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |