Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699004 | 1.00 | TERT (0.62) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8702872 | 0.96 | TERT (0.61) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8700041 | 0.90 | TERT (0.51) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8700046 | 0.90 | TERT (0.51) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8699346 | 0.83 | SLC1A3 (0.47) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8703721 | 0.82 | TERT (0.58) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8703814 | 0.81 | TERT (0.44) | TERTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8703823 | 0.81 | TERT (0.44) | TERTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9819627 | 0.81 | ALDH1A1 (0.51) | TERTMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8704202 | 0.80 | HDAC8 (0.47) | TERTMEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |