Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428964 | 0.81 | CYP3A4 (0.50) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15925192 | 0.80 | CYP1A2 (0.42) | ALDH1A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10624672 | 0.78 | IDO1 (0.49) | ALDH1A1CYP3A4CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL17844100 | 0.78 | PI4KA (0.46) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9359348 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Lithium Ion SCHEMBL9356239 | 0.76 | ALDH1A1 (0.41) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8089304 | 0.76 | CYP3A4 (0.39) | ALDH1A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15315970 | 0.76 | KDR (0.51) | ALDH1A1GRM1FLT1TSHR | |
| SCHEMBL14422762 | 0.75 | ALDH1A1 (0.40) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5638922 | 0.75 | NPC1 (0.49) | ALDH1A1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046593-A1 | NOVEL CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-22 | — | — | WO | disclosed |
| US-5541198-A | ANTISTICKING AGENTS FOR PLATELETS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0651747-B1 | CARBOSTYRYL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0651747-A1 | CARBOSTYRIL DERIVATIVES. | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026732-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |