Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428111 | 0.78 | IDO1 (0.44) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL27857839 | 0.77 | IDO1 (0.41) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL8744776 | 0.77 | LRRK2 (0.43) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL9359350 | 0.76 | IDO1 (0.43) | IDO1METAP2DCUN1D1ARRAB9A | |
| Lithium Ion SCHEMBL9356247 | 0.76 | IDO1 (0.43) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL9201299 | 0.76 | FFAR1 (0.32) | METAP2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7139325 | 0.75 | IDO1 (0.42) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL28852538 | 0.75 | IDO1 (0.42) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL11046400 | 0.74 | IDO1 (0.41) | IDO1METAP2DCUN1D1ARRAB9A | |
| SCHEMBL31325657 | 0.73 | NR1H4 (0.41) | IDO1METAP2DCUN1D1ARRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046593-A1 | NOVEL CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-22 | — | — | WO | disclosed |
| EP-0651747-A1 | CARBOSTYRIL DERIVATIVES. | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026732-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |
| US-4973588-A | IMPROVED BRAIN FUNCTION AT REDUCED OXYGEN LEVELS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0332295-A2 | Novel imidazole derivative | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |