Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | PRKACG | P22612 | 2/20 | 0.31 |
| ▸ | PRKACB | P22694 | 2/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699164 | 0.76 | IDO1 (0.44) | METAP2NPC1KDM4EMEN1MAPT | |
| SCHEMBL20054201 | 0.75 | CHRNB2 (0.33) | FFAR1AGPAT2ALDH1A1CRHR1 | |
| SCHEMBL2945910 | 0.70 | S100A4 (0.46) | FFAR1ALDH1A1AHRCYP2A6 | |
| SCHEMBL18268298 | 0.66 | S100A4 (0.42) | FFAR1ALDH1A1CYP2A6 | |
| SCHEMBL5305952 | 0.66 | NPC1 (0.41) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL27031500 | 0.65 | NT5E (0.37) | FFAR1KDM4ECRHR1 | |
| SCHEMBL5914842 | 0.65 | ADRA2A (0.49) | KDM4EMEN1KMT2ACSNK1A1ALDH1A1 | |
| SCHEMBL8744731 | 0.64 | HSP90AB1 (0.45) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19180559 | 0.63 | PTPRC (0.46) | NPC1CYP1A2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30414134 | 0.63 | ESR2 (0.42) | NPC1MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651747-A1 | CARBOSTYRIL DERIVATIVES. | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026732-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |