Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.75 |
| ▸ | NPC1 | O15118 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 4/20 | 0.64 |
| ▸ | MMP8 | P22894 | 4/20 | 0.64 |
| ▸ | MMP13 | P45452 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908000 | 0.88 | RAB9A (0.84) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL8697136 | 0.83 | RAB9A (0.85) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL2244940 | 0.81 | RAB9A (0.76) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL4146732 | 0.81 | RAB9A (0.76) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL2245219 | 0.81 | MMP2 (0.85) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL3194691 | 0.81 | RAB9A (0.76) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL16894051 | 0.81 | RAB9A (0.76) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL2243126 | 0.80 | RAB9A (1.00) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL4088004 | 0.79 | RAB9A (0.77) | RAB9ANPC1MAPTMCL1ATM | |
| SCHEMBL2244223 | 0.78 | MMP2 (1.00) | RAB9ANPC1MAPTMCL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |