Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | AOC2 | O75106 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699333 | 0.85 | AOC2 (0.47) | SMN1; SMN2AOC2MEN1KMT2AALDH1A1 | |
| SCHEMBL8183727 | 0.80 | AOC2 (0.43) | SMN1; SMN2AOC2MAPT | |
| SCHEMBL8704334 | 0.80 | AOC2 (0.43) | SMN1; SMN2AOC2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8704321 | 0.79 | AOC2 (0.42) | SMN1; SMN2PRSS1PRSS2PRSS3AOC2 | |
| Hydrochloric Acid SCHEMBL8704455 | 0.79 | AOC2 (0.42) | SMN1; SMN2AOC2MAPT | |
| Hydrochloric Acid SCHEMBL8707259 | 0.77 | AOC2 (0.41) | SMN1; SMN2AOC2MEN1KMT2AALDH1A1 | |
| SCHEMBL1387889 | 0.76 | CYP3A4 (0.44) | SMN1; SMN2CYP3A4TSHRPRSS1PRSS2 | |
| SCHEMBL8300855 | 0.76 | AOC2 (0.43) | SMN1; SMN2PRSS1PRSS2PRSS3AOC2 | |
| SCHEMBL8699717 | 0.76 | AOC2 (0.40) | SMN1; SMN2TSHRAOC2MEN1KMT2A | |
| SCHEMBL7826626 | 0.76 | MEN1 (0.48) | SMN1; SMN2ALOX5MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | claimed |
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |