Maslinic Acid

Maslinic Acid

SCHEMBL869930

CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC(O)[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 8/20 1.00
▸ PTPN2 P17706 4/20 1.00
▸ AKR1B10 O60218 3/20 1.00
▸ GPBAR1 Q8TDU6 3/20 1.00
▸ PYGM P11217 1/20 1.00
▸ AKR1B1 P15121 1/20 1.00
▸ ALOX5 P09917 2/20 0.83
▸ EGLN2 Q96KS0 1/20 0.80
▸ EGLN1 Q9GZT9 1/20 0.80
▸ EGLN3 Q9H6Z9 1/20 0.80
▸ P4HTM Q9NXG6 1/20 0.80
▸ POLB P06746 3/20 0.78
▸ PSMB11 A5LHX3 2/20 0.78
▸ PSMA7 O14818 2/20 0.78
▸ PLA2G1B P04054 2/20 0.78
▸ PTPRC P08575 2/20 0.78
▸ PTPRF P10586 2/20 0.78
▸ F3 P13726 2/20 0.78
▸ PSMB1 P20618 2/20 0.78
▸ CES1 P23141 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maslinic Acid SCHEMBL18420546 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL5797455 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL14132395 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL24627035 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL5797458 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL23716504 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL12638707 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL22026389 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL21296155 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM
Maslinic Acid SCHEMBL570425 1.00 PTPN1 (1.00) PTPN1PTPN2AKR1B10GPBAR1PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114558061-A Loquat leaf extract and preparation method and application thereof 浙江大学 2022-05-31 — — CN claimed
CN-102573865-B Composition for preventing and treating erythrocyte aggregation 基因雷克斯制药有限公司 2016-08-24 — — CN claimed
CN-102497873-B Compositions and methods for increasing life and health GENEREX PHARMACEUTICALS, INC. (CN) 2016-04-13 — — CN claimed
EP-1569668-B1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF LEAD BILLION LTD (CN) 2011-07-20 — — EP claimed
EP-1569668-A4 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF UNIV HONG KONG CHINESE (HK) 2009-07-01 — — EP claimed
US-7387801-B2 Organic extract of Geum japonicum Thunb variant and use thereof THE CHINESE UNIVERSITY OF HONG KONG (CN) 2008-06-17 — — US claimed
EP-1773313-A4 CONTROL OF BIOFILM FORMATION ELDRIDGE GARY R (US) 2007-11-07 — — EP claimed
EP-1773313-A2 CONTROL OF BIOFILM FORMATION Eldridge, Gary R. (US) 2007-04-18 — — EP claimed
US-20070014739-A1 Compositions and methods for controlling biofilms and bacterial infections SEQUOIA SCIENCES, INC. 2007-01-18 — — US claimed
US-20060264411-A1 Control of biofilm formation SEQUOIA SCIENCES, INC. 2006-11-23 — — US claimed
US-20060134229-A1 Organic extract of geum japonicum thunb variant and use thereof CHINESE UNIVERSITY OF HONG KONG (CN) 2006-06-22 — — US claimed
WO-2006019881-A2 COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS AND BACTERIAL INFECTIONS ELDRIDGE GARY R (US) 2006-02-23 — — WO claimed
WO-2006010147-A2 CONTROL OF BIOFILM FORMATION ELDRIDGE GARY R (US) 2006-01-26 — — WO claimed
EP-1569668-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (HK) 2005-09-07 — — EP claimed
WO-2004052381-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2004-06-24 — — WO claimed
CN-114558061-B Loquat leaf extract and preparation method and application thereof 浙江大学 2023-04-04 — — CN disclosed
CN-114558061-A Loquat leaf extract and preparation method and application thereof 浙江大学 2022-05-31 — — CN disclosed
WO-2004052381-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2004-06-24 — — WO disclosed
WO-2003043645-A1 COMPOSITIONS COMPRISING ORGANIC EXTRACTS OF GEUM JAPONICUM THUNB VAR. AND THE USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2003-05-30 — — WO disclosed
US-5916919-A TRITERPENES DALHOUSIE UNIVERSITY (CA) 1999-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070014739-A1 Compositions and methods for controlling biofilms and bacterial infections RHOA, ALOX5, BLVRB PTPN1 1158/4885PTPN2 1629/4885AKR1B10 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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