Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RBP4 | P02753 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700254 | 0.88 | GAA (0.56) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL8700453 | 0.86 | RBP4 (0.56) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL8088095 | 0.85 | KMT2A (0.40) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL6953333 | 0.84 | GAA (0.47) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL6964825 | 0.83 | RBP4 (0.45) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL8699457 | 0.82 | MAPT (0.56) | GAARBP4KMT2AMAPTHTT | |
| SCHEMBL6956179 | 0.82 | GAA (0.58) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL8704990 | 0.81 | KMT2A (0.56) | PANK3RBP4KMT2AMAPTHTT | |
| SCHEMBL8703760 | 0.80 | GAA (0.53) | PANK3GAARBP4KMT2AMAPT | |
| SCHEMBL6955682 | 0.80 | KMT2A (0.45) | GAARBP4KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |