Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.64 |
| ▸ | HTR1D | P28221 | 4/20 | 0.60 |
| ▸ | HTR1B | P28222 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | GABRE | P78334 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699573 | 1.00 | HTR6 (0.64) | HTR6HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL8506286 | 0.88 | SLC6A4 (0.67) | HTR6HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL8506646 | 0.84 | HTR6 (0.67) | HTR6HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL8506642 | 0.84 | HTR6 (0.67) | HTR6HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL8789712 | 0.84 | HTR6 (0.56) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL8789718 | 0.84 | HTR6 (0.56) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL8886514 | 0.83 | HTR6 (0.55) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL8915205 | 0.83 | HTR6 (0.53) | HTR6HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL8914713 | 0.83 | HTR6 (0.53) | HTR6HTR1BHTR1ASLC6A4HTR2C | |
| SCHEMBL8874433 | 0.83 | HTR6 (0.62) | HTR6HTR1DHTR1BHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | disclosed |
| WO-1998027089-A1 | 5-ALKYL INDOLE COMPOUNDS AS 5-HT1D-LIKE LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-06-25 | — | — | WO | disclosed |