Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.46 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702221 | 0.89 | SLC9A1 (0.37) | SLC9A1SLC9A3SLC9A2KMT2ACA1 | |
| SCHEMBL8703295 | 0.85 | HTT (0.41) | SLC9A1SLC9A3SLC9A2MAPTKDM4E | |
| SCHEMBL8700610 | 0.83 | SLC9A1 (0.49) | SLC9A1SLC9A3SLC9A2KMT2ACA1 | |
| SCHEMBL6927272 | 0.82 | SLC9A1 (0.63) | SLC9A1SLC9A3SLC9A2KMT2AMAPT | |
| SCHEMBL8703959 | 0.82 | PSEN1 (0.39) | SLC9A1SLC9A3SLC9A2TSHR | |
| SCHEMBL8701738 | 0.81 | SLC9A1 (0.49) | SLC9A1SLC9A3SLC9A2KMT2AKDM4E | |
| SCHEMBL8702119 | 0.80 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2KMT2ACA1 | |
| SCHEMBL8444301 | 0.80 | SLC9A1 (0.71) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8574698 | 0.78 | HTT (0.40) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL8707552 | 0.78 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |