Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.49 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704148 | 0.88 | EED (0.40) | SLC9A1SLC9A3SLC9A2L3MBTL1KMT2A | |
| SCHEMBL6927272 | 0.85 | SLC9A1 (0.63) | SLC9A1SLC9A3SLC9A2KMT2AKDM4E | |
| SCHEMBL8700610 | 0.84 | SLC9A1 (0.49) | SLC9A1SLC9A3SLC9A2L3MBTL1KMT2A | |
| SCHEMBL8704442 | 0.84 | AAK1 (0.45) | GAANR1I2HTTFGFR1SRC | |
| SCHEMBL8444811 | 0.81 | SLC9A1 (0.72) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8702119 | 0.81 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2L3MBTL1KMT2A | |
| SCHEMBL8699634 | 0.81 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2L3MBTL1KMT2A | |
| SCHEMBL8700069 | 0.81 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2L3MBTL1KMT2A | |
| SCHEMBL8707552 | 0.81 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2KMT2AGAA | |
| SCHEMBL8705014 | 0.80 | PSEN1 (0.43) | NR1I2FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |