Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702841 | 0.80 | PSMB8 (0.51) | MAPTALDH1A1HPGDPSMB8NPC1 | |
| SCHEMBL11535872 | 0.72 | NPC1 (0.53) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL8274520 | 0.69 | MAPT (0.52) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL19475890 | 0.68 | ALDH1A1 (0.51) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL11701100 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL11701110 | 0.66 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL10174797 | 0.66 | CTNNB1 (0.66) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL11006494 | 0.66 | ALDH1A1 (0.46) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL11243754 | 0.65 | PLA2G1B (0.49) | MAPTALDH1A1ALOX15PSMD14MMP2 | |
| SCHEMBL256810 | 0.64 | ALOX15 (0.57) | MAPTALDH1A1ALOX15PSMD14MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |