Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475521 | 1.00 | ADRA2B (0.53) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL27998892 | 0.98 | ADRA2B (0.52) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL11599991 | 0.86 | ADRA2B (0.52) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL10960394 | 0.84 | ADRA2B (0.63) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL465333 | 0.82 | ALDH1A1 (0.46) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL4432874 | 0.82 | TSHR (0.46) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL6278058 | 0.81 | SLC6A2 (0.50) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL27521397 | 0.81 | MAPT (0.44) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL135869 | 0.79 | ADRA2B (0.62) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL15146911 | 0.79 | ADRA2B (0.57) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |