Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702387 | 0.88 | CYP19A1 (0.55) | CYP26A1CYP19A1ALDH1A1NPC1RAB9A | |
| SCHEMBL8702471 | 0.88 | CYP19A1 (0.57) | CYP26A1CYP19A1LMNANPC1RAB9A | |
| SCHEMBL8697118 | 0.88 | CYP19A1 (0.55) | CYP26A1CYP19A1NPC1RAB9A | |
| SCHEMBL28559346 | 0.87 | RAB9A (0.44) | CYP26A1ALDH1A1LMNATHRBNPC1 | |
| SCHEMBL8697788 | 0.85 | CYP19A1 (0.60) | CYP26A1CYP19A1 | |
| SCHEMBL24621094 | 0.79 | CYP19A1 (0.42) | CYP26A1CYP19A1METAP2LMNANPC1 | |
| SCHEMBL24621095 | 0.79 | CYP19A1 (0.42) | CYP26A1CYP19A1ALDH1A1NPC1RAB9A | |
| SCHEMBL8697486 | 0.78 | CYP19A1 (0.46) | CYP26A1CYP19A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29707672 | 0.78 | CYP19A1 (0.52) | CYP26A1CYP19A1ALDH1A1LMNATHRB | |
| SCHEMBL28573406 | 0.78 | NQO1 (0.46) | CYP26A1CYP19A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |