Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700537 | 0.85 | CYP19A1 (0.47) | CYP19A1CYP26A1CYP3A4 | |
| SCHEMBL8697118 | 0.84 | CYP19A1 (0.55) | CYP19A1NPC1CYP26A1RAB9ATSHR | |
| SCHEMBL8699998 | 0.78 | CYP26A1 (0.44) | CYP19A1NPC1CYP26A1RAB9ASLC6A2 | |
| SCHEMBL8697855 | 0.74 | CYP19A1 (0.40) | CYP19A1NPC1RAB9AIDO1TDO2 | |
| SCHEMBL8702186 | 0.74 | CYP19A1 (0.47) | CYP19A1NPC1CYP26A1RAB9ATSHR | |
| SCHEMBL8702387 | 0.74 | CYP19A1 (0.55) | CYP19A1NPC1CYP26A1RAB9ACYP3A4 | |
| SCHEMBL8702471 | 0.74 | CYP19A1 (0.57) | CYP19A1NPC1CYP26A1RAB9ATSHR | |
| SCHEMBL8697755 | 0.72 | CYP19A1 (0.73) | CYP19A1CYP26A1CYP3A4 | |
| SCHEMBL24621095 | 0.71 | CYP19A1 (0.42) | CYP19A1NPC1CYP26A1RAB9A | |
| SCHEMBL24621094 | 0.71 | CYP19A1 (0.42) | CYP19A1NPC1CYP26A1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |