Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.38 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707619 | 0.87 | SLC9A1 (0.41) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8704354 | 0.82 | SLC9A1 (0.53) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8700682 | 0.82 | SLC9A1 (0.39) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8705330 | 0.82 | PSEN1 (0.37) | — | |
| SCHEMBL9022321 | 0.81 | SLC9A1 (0.37) | SLC9A1 | |
| SCHEMBL8706145 | 0.81 | SLC9A1 (0.43) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8700153 | 0.79 | SLC9A1 (0.39) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8446140 | 0.78 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8530997 | 0.77 | SLC9A1 (0.50) | SLC9A1 | |
| SCHEMBL8706252 | 0.77 | HPGD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |
| EP-0699666-A1 | Heterocyclic substituted benzoylguanidine | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |