Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360612 | 0.87 | PDE4A (0.35) | — | |
| SCHEMBL8700401 | 0.86 | SLC9A1 (0.43) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8704354 | 0.85 | SLC9A1 (0.53) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8706145 | 0.84 | SLC9A1 (0.43) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8700000 | 0.82 | SLC9A1 (0.38) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8699331 | 0.81 | HTT (0.44) | — | |
| SCHEMBL8700153 | 0.80 | SLC9A1 (0.39) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8444399 | 0.77 | SLC9A1 (0.55) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8704001 | 0.77 | SLC9A1 (0.56) | SLC9A1 | |
| SCHEMBL9022321 | 0.76 | SLC9A1 (0.37) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |
| EP-0699666-A1 | Heterocyclic substituted benzoylguanidine | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |