SCHEMBL8700028

SCHEMBL8700028

O=C1NC(=O)C(N=CC=Cc2ccc([N+](=O)[O-])o2)N1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.47
KMT2A Q03164 11/20 0.46
TDP1 Q9NUW8 9/20 0.46
KDM4E B2RXH2 6/20 0.46
HTT P42858 4/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
RECQL P46063 2/20 0.46
HSP90AA1 P07900 1/20 0.46
THRB P10828 1/20 0.46
TNNI3 P19429 1/20 0.46
MAPK1 P28482 1/20 0.46
TNNT2 P45379 1/20 0.46
TNNC1 P63316 1/20 0.46
MCL1 Q07820 1/20 0.46
MEN1 O00255 9/20 0.44
POLB P06746 8/20 0.44
CASP6 P55212 3/20 0.44
CCR6 P51684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538746 0.85 LMNA (0.54) KMT2ATDP1KDM4EHTTNPC1
SCHEMBL13044215 0.73 MAPT (0.49) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL16742056 0.73 MAPT (0.49) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL26178930 0.72 KMT2A (0.56) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL10683254 0.72 KMT2A (0.56) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL30423130 0.70 KMT2A (0.76) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL13044216 0.69 SLC2A1 (0.63) SLC2A1KMT2ATDP1KDM4EHTT
SCHEMBL16742035 0.69 SLC2A1 (0.63) SLC2A1KMT2ATDP1KDM4EHTT
Furazidin SCHEMBL8703982 0.69 TDP1 (0.74) SLC2A1KMT2ATDP1KDM4EHTT
Furazidin SCHEMBL3194895 0.69 TDP1 (0.74) SLC2A1KMT2ATDP1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998041520-A1 A PROCESS FOR THE PREPARATION OF FURAZIDIN ADAMED SP. Z O.O. (PL) 1998-09-24 WO disclosed