Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700028 | 0.85 | SLC2A1 (0.47) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL2911361 | 0.81 | MAPT (0.58) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL16268566 | 0.80 | MAPT (0.57) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL2987018 | 0.76 | KMT2A (0.49) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL2903627 | 0.73 | KMT2A (0.52) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL16742056 | 0.71 | MAPT (0.49) | LMNATDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL13044215 | 0.71 | MAPT (0.49) | LMNATDP1ALDH1A1MAPTKDM4E | |
| Nifuroxime SCHEMBL5025023 | 0.70 | LMNA (0.76) | LMNATDP1ALDH1A1MAPTKDM4E | |
| Nifuroxime SCHEMBL465512 | 0.70 | LMNA (0.76) | LMNATDP1ALDH1A1MAPTKDM4E | |
| Nifuroxime SCHEMBL465511 | 0.70 | LMNA (0.76) | LMNATDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198467-A1 | 5-NITROFURFURAL DERIVATIVES | NORSK HYDRO ASA (NO) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001002412-A1 | 5-NITROFURFURAL DERIVATIVES | NORSK HYDRO ASA (NO) | 2001-01-11 | — | — | WO | disclosed |
| WO-1997019930-A1 | PROCESS FOR PRODUCING 1-AMINOHYDANTOIN | LONZA AG (CH) | 1997-06-05 | — | — | WO | disclosed |