Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | CCR9 | P51686 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697267 | 0.89 | CCR2 (0.59) | CCR2PLA2G10PPARGSERPINE1GPR35 | |
| SCHEMBL8700066 | 0.89 | CCR2 (0.64) | CCR2PPARGSERPINE1GPR35CCR9 | |
| SCHEMBL8696938 | 0.88 | CCR2 (0.66) | CCR2PLA2G10PPARGSERPINE1GPR35 | |
| SCHEMBL8698509 | 0.86 | CCR2 (0.58) | CCR2PLA2G10PPARGSERPINE1 | |
| SCHEMBL8700281 | 0.85 | CCR2 (0.56) | CCR2PLA2G10PPARGSERPINE1 | |
| SCHEMBL8697266 | 0.83 | CCR2 (0.59) | CCR2PLA2G10PPARGSERPINE1GPR35 | |
| SCHEMBL8699485 | 0.80 | CCR2 (0.62) | CCR2PLA2G10PPARGSERPINE1 | |
| SCHEMBL8791999 | 0.79 | ADRB2 (0.48) | CCR2SERPINE1 | |
| SCHEMBL5378162 | 0.78 | CCR2 (1.00) | CCR2PLA2G10GPR35F10 | |
| SCHEMBL8698044 | 0.78 | CCR2 (0.64) | CCR2PLA2G10PPARGSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |