Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8706081 | 0.99 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL4583569 | 0.82 | TP53 (0.70) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL8703800 | 0.80 | KAT6A (0.56) | SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8700513 | 0.79 | KAT6A (0.55) | SMN1; SMN2LMNA | |
| SCHEMBL16355148 | 0.78 | KMT2A (0.79) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL939911 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL31175292 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL19464486 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53KMT2AMEN1EPHX2 | |
| SCHEMBL8705516 | 0.77 | AOC2 (0.68) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL334915 | 0.77 | TP53 (0.71) | SMN1; SMN2TP53KMT2AMEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |