Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PRCP | P42785 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15918786 | 0.83 | ACACB (0.55) | HPGDACACBALDH1A1 | |
| SCHEMBL1697683 | 0.81 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL1697681 | 0.81 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL10117995 | 0.81 | ALDH1A1 (0.58) | HPGDACACBKMT2AMEN1ALDH1A1 | |
| SCHEMBL12436366 | 0.81 | ALDH1A1 (0.58) | HPGDACACBKMT2AMEN1ALDH1A1 | |
| SCHEMBL2651517 | 0.81 | GAA (0.58) | GAAHPGDSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL7674958 | 0.81 | GAA (0.58) | GAAHPGDSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL10117998 | 0.81 | ALDH1A1 (0.58) | HPGDACACBKMT2AMEN1ALDH1A1 | |
| SCHEMBL22279548 | 0.81 | GAA (0.58) | GAAHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6392377 | 0.81 | GAA (0.58) | GAAHPGDSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998040362-A1 | SUBSTITUTED ARYLALKYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |