Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696579 | 0.84 | MAOB (0.46) | MAOBMAOAF2RL3PTPRCPTPN1 | |
| SCHEMBL8702189 | 0.76 | ATM (0.36) | RAB9ANPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8702207 | 0.75 | PIK3R1 (0.36) | MAOBRAB9ANPC1MAPTKDM4E | |
| SCHEMBL8704175 | 0.75 | CYP2A6 (0.34) | F2RL3METAP2RAB9ANPC1MAPT | |
| SCHEMBL19180722 | 0.72 | MAOB (0.56) | MAOBMAOAPTPRCPTPN1METAP2 | |
| SCHEMBL8700006 | 0.70 | MAOB (0.48) | MAOBMAOAF2RL3PTPRCPTPN1 | |
| SCHEMBL8696314 | 0.69 | CYP19A1 (0.41) | MAOBMAOAF2RL3PTPRCPTPN1 | |
| SCHEMBL12854020 | 0.69 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1METAP2 | |
| SCHEMBL61411 | 0.69 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1METAP2 | |
| SCHEMBL24621094 | 0.67 | CYP19A1 (0.42) | METAP2NPC1KDM4ECYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |