Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698099 | 0.83 | KCNA5 (0.36) | ATMRAB9ANPC1KCNA5KCNH2 | |
| SCHEMBL8698606 | 0.78 | ATM (0.32) | ATM | |
| SCHEMBL8702207 | 0.77 | PIK3R1 (0.36) | RAB9ANPC1CYP1A2CASP1ALDH1A1 | |
| SCHEMBL8700378 | 0.76 | MAOB (0.46) | RAB9ANPC1CYP1A2ALDH1A1HPGD | |
| SCHEMBL8698118 | 0.67 | CYP11B1 (0.33) | ATMHPGDNQO2CCNCCDK8 | |
| SCHEMBL4340667 | 0.66 | NQO2 (0.47) | CYP1A2CASP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11136545 | 0.65 | ATM (0.44) | ATMKCNA5KCNH2ALDH1A1HPGD | |
| SCHEMBL76097 | 0.65 | CYP2E1 (0.58) | RAB9ANPC1CYP1A2CASP1ALDH1A1 | |
| SCHEMBL21249436 | 0.61 | ALDH1A1 (0.62) | RAB9ANPC1CYP1A2ALDH1A1HPGD | |
| SCHEMBL28311858 | 0.61 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1HPGDNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |