Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893071 | 0.86 | RAB9A (0.42) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699929 | 0.85 | CYP19A1 (0.53) | CYP19A1NPC1RAB9ATSHRMAPK1 | |
| SCHEMBL8696810 | 0.83 | CYP19A1 (0.52) | CYP19A1NPC1RAB9AKMT2AACHE | |
| SCHEMBL10363747 | 0.83 | CYP26A1 (0.52) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24620883 | 0.80 | CYP19A1 (0.46) | CYP19A1NPC1RAB9ATSHRMAPK1 | |
| SCHEMBL29707753 | 0.80 | CYP19A1 (0.52) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10542031 | 0.80 | CYP19A1 (0.52) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28561380 | 0.80 | CYP19A1 (0.52) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8697855 | 0.80 | CYP19A1 (0.40) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10362213 | 0.80 | APP (0.43) | CYP19A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |
| EP-0257171-B1 | (BENZOFURAN-2-YL)IMIDAZOLES HAVING PHARMACEUTICAL ACTIVITY, THEIR SALTS AND RELEVANT PRODUCTION PROCESSES | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1990-08-29 | — | — | EP | disclosed |
| US-4800208-A | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI S.A.S. (IT) | 1989-01-24 | — | — | US | disclosed |