Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443254 | 0.85 | PPARG (0.66) | PPARGAGTR2AGTR1 | |
| SCHEMBL9195236 | 0.84 | PPARG (0.64) | PPARGAGTR2AGTR1 | |
| SCHEMBL9192065 | 0.83 | PPARG (0.63) | PPARGAGTR2AGTR1 | |
| SCHEMBL9194185 | 0.83 | PPARG (0.63) | PPARGAGTR2AGTR1 | |
| SCHEMBL9192150 | 0.83 | PPARG (0.63) | PPARGAGTR2AGTR1 | |
| SCHEMBL9851543 | 0.83 | AGTR1 (0.66) | PPARGAGTR2AGTR1 | |
| SCHEMBL9704682 | 0.82 | AGTR2 (0.70) | PPARGAGTR2AGTR1 | |
| Dimethylamine SCHEMBL9192520 | 0.82 | PPARG (0.62) | PPARGAGTR2AGTR1 | |
| SCHEMBL9193729 | 0.82 | PPARG (0.62) | PPARGAGTR2AGTR1 | |
| SCHEMBL9197325 | 0.82 | PPARG (0.88) | PPARGAGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798364-A | ANGIOTENSIN II ANTAGONIST, USEFUL FOR TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-08-25 | — | — | US | disclosed |
| US-5321137-A | Process for the preparation of imidazopyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-14 | — | — | US | disclosed |