Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 19/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699090 | 0.90 | EDNRB (0.75) | EDNRB | |
| SCHEMBL8703164 | 0.89 | EDNRB (0.63) | EDNRB | |
| SCHEMBL8699087 | 0.83 | EDNRB (0.79) | EDNRB | |
| SCHEMBL8698304 | 0.82 | EDNRB (0.75) | EDNRB | |
| SCHEMBL8804970 | 0.78 | EDNRB (0.72) | EDNRB | |
| SCHEMBL8700449 | 0.77 | EDNRB (0.49) | EDNRB | |
| SCHEMBL8698300 | 0.76 | EDNRB (0.80) | EDNRB | |
| SCHEMBL8804575 | 0.75 | EDNRB (0.66) | EDNRB | |
| SCHEMBL6314933 | 0.74 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8804018 | 0.74 | EDNRB (0.86) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042709-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |