Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517437 | 0.84 | CA1 (0.36) | — | |
| SCHEMBL8697120 | 0.80 | — | — | |
| SCHEMBL7539413 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL8698217 | 0.72 | MAPT (0.42) | — | |
| SCHEMBL27627276 | 0.70 | L3MBTL1 (0.44) | L3MBTL1NNMTSIRT3TDP1 | |
| SCHEMBL9487223 | 0.70 | KDM4E (0.35) | L3MBTL1TDP1 | |
| SCHEMBL4339765 | 0.70 | ALDH1A1 (0.36) | L3MBTL1TDP1 | |
| SCHEMBL8696273 | 0.70 | MAOB (0.41) | — | |
| SCHEMBL7520417 | 0.69 | TDP1 (0.46) | TDP1 | |
| SCHEMBL22023652 | 0.68 | PARP1 (0.42) | L3MBTL1SIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831073-A | Ion triggered alkylation of biological targets by silyloxy aromatic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-11-03 | — | — | US | disclosed |
| US-5493012-A | Ion triggered alkylation of biological targets by silyloxy aromatic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-02-20 | — | — | US | disclosed |