⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326680 | 0.82 | — | — | |
| SCHEMBL9744563 | 0.82 | — | — | |
| SCHEMBL14874232 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28684964 | 0.80 | TBXAS1 (0.53) | — | |
| SCHEMBL28726885 | 0.77 | — | — | |
| SCHEMBL16371567 | 0.76 | TBXAS1 (0.48) | — | |
| SCHEMBL2884168 | 0.76 | — | — | |
| SCHEMBL83887 | 0.76 | — | — | |
| SCHEMBL447733 | 0.76 | — | — | |
| SCHEMBL10529099 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543145-A | C Met kinases suppression 5 benzoic acid amides derivant of agent 3 (4 fluorophenyl) pyrimidone, preparation method and application | 山西医科大学 | 2017-03-29 | — | — | CN | claimed |
| CN-103003274-A | Pyrrolopyridine inhibitors of kinases | ABBVIE INC | 2013-03-27 | — | — | CN | claimed |
| CN-101180275-A | Tetrahydroindolone and tetrahydroindazolone derivatives | SERENEX INC (US) | 2008-05-14 | — | — | CN | claimed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| EP-0132101-A1 | 2-Heterocycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-23 | — | — | EP | claimed |
| CN-112028870-B | Compound with benzyloxy aromatic ring structure, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-11-05 | — | — | CN | disclosed |
| CN-112028870-A | Compound with benzyloxy aromatic ring structure, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-04 | — | — | CN | disclosed |
| CN-104876936-B | The preparation of pyrrolones and pyrazole compound and the purposes as medicine | 中国人民解放军第二军医大学 | 2018-01-30 | — | — | CN | disclosed |
| CN-106543145-A | C Met kinases suppression 5 benzoic acid amides derivant of agent 3 (4 fluorophenyl) pyrimidone, preparation method and application | 山西医科大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-104876936-A | Preparation of 2-hydroxy-1, 2-di-2-pyridylethanone and pyrazole class compound and application as medicine | UNIV PLA 2ND MILITARY MEDICAL | 2015-09-02 | — | — | CN | disclosed |
| CN-101180275-B | Tetrahydroindolone and tetrahydroindazolone derivatives | SERENEX INC | 2014-09-10 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |
| CN-1346355-A | Novel inhibitors of farnesyl-protein transferase | SCHERING CORP (US) | 2002-04-24 | — | — | CN | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| CN-1105363-A | Quinoline or quinazoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-07-19 | — | — | CN | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |
| EP-0132101-A1 | 2-Heterocycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-23 | — | — | EP | disclosed |