Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705064 | 0.91 | HTR1A (0.52) | RBP4HTR1AHTR1DHTR1BKMT2A | |
| SCHEMBL8699470 | 0.90 | KMT2A (0.51) | RBP4HTR1AHTR1DHTR1BKMT2A | |
| SCHEMBL8699402 | 0.90 | KMT2A (0.49) | RBP4KMT2AGAAP2RY12MAPT | |
| SCHEMBL8705983 | 0.90 | MAPT (0.57) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8701376 | 0.90 | RBP4 (0.48) | RBP4KMT2AGAAP2RY12MAPT | |
| SCHEMBL8704966 | 0.89 | RBP4 (0.48) | RBP4HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8702290 | 0.89 | RBP4 (0.48) | RBP4KMT2AGAAP2RY12MAPT | |
| SCHEMBL8704636 | 0.89 | KMT2A (0.57) | RBP4HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL8705260 | 0.89 | RBP4 (0.55) | RBP4KMT2AGAAP2RY12MAPT | |
| SCHEMBL8699044 | 0.89 | KDM4E (0.51) | RBP4HTR7KMT2AP2RY12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |