Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.32 |
| ▸ | MTOR | P42345 | 3/20 | 0.31 |
| ▸ | PRKDC | P78527 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707325 | 0.76 | CA12 (0.40) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL25919645 | 0.76 | ENPP2 (0.38) | PIK3CAATRMTORPTGS1RORC | |
| SCHEMBL7809110 | 0.75 | ALOX5 (0.47) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL7807428 | 0.75 | ALOX5 (0.47) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL1599387 | 0.74 | ALOX5 (0.42) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL8694739 | 0.73 | ALOX5 (0.46) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL1598547 | 0.73 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7807402 | 0.72 | CA12 (0.35) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL1599453 | 0.71 | ALOX5 (0.41) | HDAC3HDAC1HDAC2HDAC6ALOX5 | |
| SCHEMBL23405430 | 0.71 | ATR (0.36) | PIK3CAATRMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753682-A | Imidazole lipoxygenase inhibitors | PFIZER INC. (US) | 1998-05-19 | — | — | US | disclosed |