Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117263 | 0.84 | GAA (0.70) | ALDH1A1LMNATSHRRECQLGAA | |
| SCHEMBL8696072 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRRECQLGAA | |
| SCHEMBL8792470 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL8696994 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRRECQLGAA | |
| SCHEMBL10031020 | 0.79 | MEN1 (0.80) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL9813414 | 0.78 | SMN1; SMN2 (0.51) | LMNATSHRRECQLGAAMEN1 | |
| SCHEMBL26581051 | 0.78 | TSHR (0.63) | ALDH1A1LMNATSHRRECQLGAA | |
| SCHEMBL26581062 | 0.78 | TSHR (0.63) | ALDH1A1LMNATSHRRECQLGAA | |
| SCHEMBL17117282 | 0.78 | TAAR1 (0.62) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8699067 | 0.78 | TRPV1 (0.78) | ALDH1A1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |