Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8696554 | 0.94 | HTR1A (0.42) | ALDH1A1KDM4EHPGDTSHRCFD | |
| SCHEMBL8696072 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTSHRCFD | |
| SCHEMBL8696208 | 0.83 | POLB (0.38) | ALDH1A1KDM4EGAAPOLBGOT1 | |
| SCHEMBL8701191 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRRECQLGAALMNA | |
| SCHEMBL9813414 | 0.78 | SMN1; SMN2 (0.51) | KDM4ETSHRRECQLGAALMNA | |
| SCHEMBL6289117 | 0.76 | GOT1 (0.59) | ALDH1A1HPGDGOT1LMNAHTR1A | |
| SCHEMBL17117263 | 0.71 | GAA (0.70) | ALDH1A1TSHRRECQLGAALMNA | |
| SCHEMBL26581051 | 0.71 | TSHR (0.63) | ALDH1A1HPGDTSHRRECQLGAA | |
| SCHEMBL26581062 | 0.71 | TSHR (0.63) | ALDH1A1HPGDTSHRRECQLGAA | |
| SCHEMBL17117282 | 0.68 | TAAR1 (0.62) | ALDH1A1KDM4EHPGDLMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |