SCHEMBL8701303

SCHEMBL8701303

CCOC(=O)CC(Cc1ccccc1)C(Oc1ccccc1)N1CCN(c2ccncc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.40
AOC3 Q16853 2/20 0.39
GFER P55789 2/20 0.38
POLB P06746 1/20 0.38
OPRM1 P35372 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
HIF1A Q16665 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
ROCK2 O75116 1/20 0.37
TP53 P04637 2/20 0.37
F10 P00742 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8631645 0.77 ITGB3 (0.54) ITGB3ITGA2BGAAATMOPRM1
SCHEMBL27442362 0.77 GAA (0.43) ITGB3ITGA2BGAAATMAOC3
SCHEMBL8890358 0.77 ITGB3 (0.57) ITGB3ITGA2BATMGFERPOLB
Hydrochloric Acid SCHEMBL8637477 0.77 GAA (0.46) ITGB3ITGA2BGAAAOC3OPRM1
SCHEMBL7401163 0.76 ITGB3 (0.50) ITGB3ITGA2BGAAATMAOC3
SCHEMBL8633583 0.76 ITGB3 (0.47) ITGB3ITGA2BGAAATMOPRM1
SCHEMBL8631650 0.75 ITGB3 (0.48) ITGB3ITGA2BGAAATMOPRM1
SCHEMBL8633587 0.74 ITGB3 (0.45) ITGB3ITGA2BGAAATMOPRM1
SCHEMBL8634059 0.74 ITGB3 (0.44) ITGB3ITGA2BGAAAOC3OPRM1
Hydrochloric Acid SCHEMBL8699382 0.73 ITGB3 (0.43) ITGB3ITGA2BGAAAOC3OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750754-A TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS ZENECA LIMITED (GB) 1998-05-12 US disclosed