Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631645 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8635826 | 0.79 | HRH3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL8681084 | 0.78 | HRH3 (0.53) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL27442362 | 0.78 | GAA (0.43) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8701303 | 0.76 | ITGB3 (0.41) | ITGB3ITGA2BHRH3HRH1ATM | |
| SCHEMBL8630600 | 0.76 | HRH3 (0.55) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8890358 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7334450 | 0.75 | HRH3 (0.57) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8888693 | 0.75 | ITGB3 (0.75) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL8637477 | 0.75 | GAA (0.46) | ITGB3ITGA2BHRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |