Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701204 | 0.84 | ALDH1A1 (0.33) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| SCHEMBL8694882 | 0.82 | ALDH1A1 (0.32) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| SCHEMBL27922015 | 0.64 | — | — | |
| SCHEMBL38660196 | 0.61 | LMNA (0.32) | — | |
| SCHEMBL10966177 | 0.55 | LMNA (0.33) | — | |
| SCHEMBL6850712 | 0.55 | FFAR4 (0.30) | — | |
| Propionic Acid SCHEMBL28116173 | 0.53 | FFAR3 (0.67) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| Butyric Acid SCHEMBL27973198 | 0.52 | FFAR3 (0.72) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| Butyric Acid SCHEMBL27921313 | 0.52 | FFAR3 (0.72) | ALDH1A1CYP19A1RXRAPPARGOXER1 | |
| Propionic Acid SCHEMBL31243331 | 0.52 | ALDH1A1 (0.54) | ALDH1A1CYP19A1RXRAPPARGOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |