Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693658 | 0.84 | HPGD (0.52) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL5885064 | 0.83 | HPGD (0.68) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL14483838 | 0.80 | HPGD (0.55) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL9778247 | 0.79 | HPGD (0.59) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL1561753 | 0.79 | HPGD (0.66) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| Anthranilic Acid SCHEMBL28965727 | 0.78 | HPGD (0.64) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL14058456 | 0.78 | HPGD (0.53) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL4863921 | 0.77 | HPGD (0.55) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL9778175 | 0.77 | HPGD (0.55) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL28761313 | 0.76 | HPGD (0.72) | ALOX15HPGDCYP1A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710319-A | Process for the preparation of substituted quinazoline-2,4-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |