Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561753 | 0.84 | HPGD (0.66) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL4559294 | 0.78 | HPGD (0.66) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL8701347 | 0.77 | ALOX15 (0.57) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL28994968 | 0.75 | TSHR (0.64) | HPGDMAPTALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL9725036 | 0.74 | HPGD (0.61) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL7870127 | 0.74 | HPGD (0.66) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL461826 | 0.74 | HPGD (0.66) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL8693658 | 0.74 | HPGD (0.52) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| Anthranilic Acid SCHEMBL28965727 | 0.74 | HPGD (0.64) | HPGDCYP1A2MAPTALOX15ALDH1A1 | |
| SCHEMBL28618627 | 0.73 | HPGD (0.64) | HPGDCYP1A2MAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080226550-A1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-7321027-B2 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1276718-B1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | HARVARD COLLEGE (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20040097735-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-05-20 | — | — | US | disclosed |
| EP-1276718-A2 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083436-A2 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226550-A1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | VHL, MEN1, NRAS | HPGD 3628/4885CYP1A2 4828/4885MAPT 4429/4885 |
| US-20040097735-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | VHL, MEN1, NRAS | HPGD 3628/4885CYP1A2 4828/4885MAPT 4429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.