Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14483838 | 0.85 | HPGD (0.55) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8606998 | 0.85 | ALDH1A1 (0.51) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5885064 | 0.82 | HPGD (0.68) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11387797 | 0.81 | HPGD (0.55) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9778203 | 0.79 | ALOX5 (0.43) | HPGDPOLBCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8701347 | 0.77 | ALOX15 (0.57) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12006630 | 0.77 | ALDH1A1 (0.55) | HPGDPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9875991 | 0.76 | CYP1A2 (0.56) | POLBCYP1A2MAPTALDH1A1RAB9A | |
| SCHEMBL823157 | 0.76 | CYP1A2 (0.56) | CYP1A2MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL9778247 | 0.75 | HPGD (0.59) | HPGDPOLBCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5009934-A | Process for preparing poly-(imidesiloxanes) | WACKER-CHEMIE GMBH (DE) | 1991-04-23 | — | — | US | disclosed |