Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252325 | 0.90 | TP53 (0.48) | TP53ALDH1A1CYP2A6ALOX5PTGS1 | |
| SCHEMBL16105872 | 0.86 | TP53 (0.59) | TP53CASP3SENP7ALDH1A1CYP1A2 | |
| SCHEMBL6547298 | 0.86 | TP53 (0.59) | TP53CASP3SENP7ALDH1A1CYP1A2 | |
| SCHEMBL16105660 | 0.86 | TP53 (0.59) | TP53CASP3SENP7ALDH1A1CYP1A2 | |
| SCHEMBL8515931 | 0.82 | TP53 (0.54) | TP53CASP3SENP7ALDH1A1CYP2A6 | |
| Styrene SCHEMBL9795236 | 0.82 | ALDH1A1 (0.61) | TP53CASP3SENP7ALDH1A1CYP2A6 | |
| SCHEMBL8948448 | 0.82 | MAOB (0.61) | TP53CASP3SENP7ALDH1A1ALOX5 | |
| SCHEMBL18240775 | 0.80 | TP53 (0.47) | TP53CASP3SENP7CYP1A2ALOX5 | |
| SCHEMBL18240677 | 0.79 | ALDH1A1 (0.42) | TP53ALDH1A1ALOX5PTGS1PTGS2 | |
| SCHEMBL18240755 | 0.79 | LMNA (0.57) | ALDH1A1ALOX5PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |
| US-5840684-A | Glycopeptide antibiotic derivatives | ELI LILLY AND COMPANY (US) | 1998-11-24 | — | — | US | disclosed |