Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195731 | 0.98 | NPC1 (0.70) | NPC1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10195733 | 0.85 | KMT2A (0.57) | NPC1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10195739 | 0.84 | FKBP1A (0.72) | ALDH1A1KMT2ATSHR | |
| SCHEMBL13900106 | 0.83 | NPC1 (0.68) | NPC1TDP1ALDH1A1NAAAPOLB | |
| SCHEMBL16679367 | 0.83 | NPC1 (0.68) | NPC1TDP1ALDH1A1NAAAPOLB | |
| SCHEMBL6285963 | 0.83 | NPC1 (0.96) | NPC1TDP1MEN1KMT2ANAAA | |
| SCHEMBL12082384 | 0.83 | SMN1; SMN2 (0.70) | NPC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17087869 | 0.83 | NPC1 (0.96) | NPC1TDP1MEN1KMT2ANAAA | |
| SCHEMBL23241211 | 0.83 | POLB (0.55) | NPC1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3126004 | 0.81 | NPC1 (0.70) | NPC1TDP1NAAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |