SCHEMBL8701490

SCHEMBL8701490

Cc1cccc(C(O)=S)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 5/20 0.46
MAPT P10636 2/20 0.46
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
KMT2A Q03164 5/20 0.43
MEN1 O00255 3/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
LMNA P02545 2/20 0.43
AKR1B10 O60218 1/20 0.43
ABCB11 O95342 1/20 0.43
DHFR P00374 1/20 0.43
MPO P05164 1/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM1 P11229 1/20 0.43
AKR1B1 P15121 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL29034437 0.90 MEN1 (0.41) TRPA1ATMALDH1A1MAPTHSD17B10
Thiobenzoic Acid SCHEMBL29043761 0.88 MEN1 (0.40) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL1029641 0.80 HPGD (0.47) ALDH1A1MAPTHSD17B10KDM4EHPGD
SCHEMBL31135508 0.80 HPGD (0.47) ALDH1A1MAPTHSD17B10KDM4EHPGD
SCHEMBL8175043 0.79 TRPA1 (0.44) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL2960120 0.79 ALDH1A1 (0.63) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL9538691 0.79 TRPA1 (0.44) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL6761818 0.79 MAPT (0.53) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL28586350 0.79 MEN1 (0.42) TRPA1ATMALDH1A1MAPTHSD17B10
SCHEMBL16950882 0.78 TRPA1 (0.48) TRPA1ATMALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457409-A Chloroprene rubber composition, sulfide of the chloroprene rubber composition, and vulcanized molded article of the chloroprene rubber composition 电化株式会社 2023-07-18 CN disclosed
WO-2022078972-A1 HERBICIDE COMBINATION COMPRISING GLUFOSINATE, SAFLUFENACIL AND TRIFLUDIMOXAZIN BASF SE (DE) 2022-04-21 WO disclosed
CN-105646356-A Preparation method of sulfophenyl pyrazolone and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-06-08 CN disclosed
CN-102924352-B Method for synthesizing 4-mercaptobenzoate BEIJING INSIGHT HIGH TECHNOLOGY CO LTD 2013-11-20 CN disclosed
CN-102924352-A Method for synthesizing 4-mercaptobenzoate BEIJING INSIGHT HIGH TECHNOLOGY CO LTD 2013-02-13 CN disclosed
CN-1554750-B Subtilase variants and compositions NOVO NORDISK AS 2011-05-18 CN disclosed
CN-1165615-C Subtilase variants and compositions ŵά�Ź�˾ 2004-09-08 CN disclosed
CN-1235638-A Subtilase variants and compositions NOVO NORDISK AS (DK) 1999-11-17 CN disclosed
CN-1193346-A Modified enzyme with lipolytic activity NOVO NORDISK AS (DK) 1998-09-16 CN disclosed
US-5750549-A ANTIINFLAMMATORY AGENTS OR ANALGESICS MERCK & CO., INC. (US) 1998-05-12 US disclosed
CN-1084559-A Be used to remove the application of the modified poly ester of grease of fabrics PROCTER & GAMBLE (US) 1994-03-30 CN disclosed
CN-1070400-A Benzoglyoxaline FISONS PLC (GB) 1993-03-31 CN disclosed
WO-1993002077-A1 BENZIMIDAZOLES FISONS PLC (GB) 1993-02-04 WO disclosed
EP-0526033-A1 Benzimidazoles FISONS plc (GB) 1993-02-03 EP disclosed